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Search Results for " neuromuscular junction "

10

Compounds

Cat No. Product Name Synonyms Targets
T4497 Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine Others
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...
T6S0084 Tuberostemonine Tuberstemonine Parasite
1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.
T4S1876 3-Deoxyaconitine Sodium Channel
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the rele...
TP1253 Argireline Acetyl hexapeptide-3 Others
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argirelin...
T25683 Leucomyosuppressin p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2
Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.
T69158 Ambenonium chloride tetrahydrate
Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav...
T71758 Ambenonium chloride
Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav...
T36068 Brevetoxin B
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junct...
T73804 Botulinum toxin type B
Botulinum toxin type B, an antigen-specific exotoxin produced by the anaerobic bacterium Clostridium botulinum, is utilized in the study of neck dystonia. It inhibits the release of Acetylcholine from the neuromuscular j...
T75732 α-CGRP, rat TFA
α-CGRP, rat TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP, rat TFA can lead to a fall in blood pressure and an increase in heart ...
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