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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4497 | Amifampridine | 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine | Others |
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ... | |||
T6S0084 | Tuberostemonine | Tuberstemonine | Parasite |
1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction. | |||
T4S1876 | 3-Deoxyaconitine | Sodium Channel | |
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the rele... | |||
TP1253 | Argireline | Acetyl hexapeptide-3 | Others |
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argirelin... | |||
T25683 | Leucomyosuppressin | p-Glu-asp-val-asp-his-val-phe-leu-arg-phe-NH2 | |
Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction. | |||
T69158 | Ambenonium chloride tetrahydrate | ||
Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav... | |||
T71758 | Ambenonium chloride | ||
Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia grav... | |||
T36068 | Brevetoxin B | ||
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junct... | |||
T73804 | Botulinum toxin type B | ||
Botulinum toxin type B, an antigen-specific exotoxin produced by the anaerobic bacterium Clostridium botulinum, is utilized in the study of neck dystonia. It inhibits the release of Acetylcholine from the neuromuscular j... | |||
T75732 | α-CGRP, rat TFA | ||
α-CGRP, rat TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP, rat TFA can lead to a fall in blood pressure and an increase in heart ... |